The Missouri National Recreational River (MNRR) is a partnership-based park. Within the 98-mile MNRR corridor, the National Park Service works with federal, state, county, and city agencies as well as commercial interests, private citizens and public interest groups to protect park resources, provide visitor services and programs, enhancing the park's ability to carry out its mission.
Among the park's many partners are:
- U.S. Army Corps of Engineers
- U. S. Fish and Wildlife Service
- South Dakota Department of Game, Fish and Parks
- Nebraska Game and Parks Commission
- MNRR Water Trail
- Missouri River Institute at University of South Dakota