The Pacific Coast Science and Learning Center serves:
- Point Reyes National Seashore,
- Golden Gate National Recreation Area,
- Pinnacles National Park,
- Muir Woods National Monument,
- Eugene O’Neil National Historic Site,
- John Muir National Historic Site, and
- Fort Point National Historic Site.
Other partners include The Presidio Trust, the San Francisco Bay Area Inventory and Monitoring Program, and the Californian Cooperative Ecosystem Studies Unit.