Organized at Zanesville, Ohio, and mustered in May 9, 1864. Left State for Harper's Ferry, W. Va., May 9. Assigned to 3rd Separate Brigade, 8th Army Corps, Middle Department. At Maryland Heights till May 17. Guard duty in the Defences of Baltimore, Md., and guarding bridges along Philadelphia, Wilmington & Baltimore Railroad by Detachments till July. Battle of Monocacy Junction, Md., July 9. Expedition to Parkesville July 12. Companies "B" "E" "G" and "I" guard railroad at Havre de Grace July 28 to August 13. Ordered home August 13, and mustered out August 24, 1864.
Regiment lost 10 Enlisted men by disease during service.