Organized at Davenport January 31 to March 5, 1863. Moved to Sioux City, Dakota, March 16-April 26, 1863. Operations against hostile Indians about Fort Randall May and June. Moved to Fort Pierre, and duty there till July. Sully's Expedition against hostile Sioux Indians August 13-September 11. Actions at White Stone Hill September 3 and 5. Duty at Fort Sully, Fort Randall and Sioux City till June, 1864. Sully's Expedition against hostile Sioux Indians June 26-October 8. Engagement at Tah kah a kuty July 28. Two Hills, Bad Lands, Little Missouri River, August 8. Expedition from Fort Rice to relief of Fisk's Emigrant train September 11-30. Fort Rice September 27. Duty by Detachments at Fort Randall, Sioux City, Fort Berthold, Yankton and the Sioux and Winnebago Indian Agencies till October, 1865. Mustered out October 17, 1865.
Regiment lost during service 1 Officer and 21 Enlisted men killed and mortally wounded and 1 Officer and 74 Enlisted men by disease. Total 97.