Organized at Keokuk for three months and mustered in May 14, 1861. Left State for Missouri June 13. Moved from Macon City to Renick and Booneville June 15-21. Lyons' advance on Springfield, Mo., June-July. Expedition to Forsyth July 20-25. Action at Forsyth July 22. Dug Springs August 2. Battle of Wilson's Creek August 10. Retreat to Springfield, thence to Rolla. Mustered out August 20, 1861.
Regiment lost during service 1 Officer and 19 Enlisted men killed and mortally wounded, and 8 Enlisted men by disease. Total 28.