At least 21 plant species are known to be invasive at Buffalo National River. Exotic Plant Management Teams (EMPT) work in parks throughout the country to limit the spread of invasive plants and promote healthy, diverse native ecosystems. Control may be accomplished with simple hand tools to dig out specimens or require heavy machinery or chain saws to cut large trees. Limited application of specific herbicide may be required to prevent regrowth.
Recent control efforts focused on Tree of Heaven (Ailanthus altissima), Chinese Privet (Ligustrum sinense) and European Privet (Ligustrum vulgare), and Mimosa (Albizia julibrissin).