Area map of Big Bend and vicinity.
Several highways lead to Big Bend National Park: TX 118 from Alpine to Study Butte or FM 170 from Presidio to Study Butte (then 26 miles east to park headquarters) or US 90 or US 385 to Marathon (then 70 miles south to park headquarters).
Distances between towns and services are considerable. Be sure you have plenty of gas, oil, food, and water for your trip. The park has four camp stores, but supply and selection can be limited. There are also small stores in the communities outside the park. The last major shopping areas (grocery and hardware stores) are Alpine, Fort Stockton, and Del Rio.