Bison are an essential component of Yellowstone National Park because they contribute to the biological, ecological, cultural, and aesthetic purposes of the park. However, Yellowstone National Park is not a self-contained ecosystem for bison, and periodic migrations into Montana are natural events. Some bison have brucellosis and may transmit it to cattle outside the park boundaries in Montana. As bison migrate out of the park and into Montana, they move from one jurisdiction with management objectives to a different jurisdiction with different management objectives. Therefore, the cooperation of several agencies is required to fully manage the herd and the risk of transmission of brucellosis from bison to Montana domestic cattle.