The Mogan Center is a program of Lowell National Historic Park, in partnership with the University of Massachusetts Lowell. The University acts as Lowell National Historical Park's key partner in the Mogan Center through its operation of the Center for Lowell History, as well as other educational activities, including Learning in Retirement Association classes. University representatives serve on the nine-member community committee which proposes and reviews Mogan Center programs. The Center for Lowell History maintains the holdings of several important archival collections including the Lowell Historical Society, the Boston and Maine Railroad Historical Society and the University of Massachusetts Lowell.

The Angkor Dance Troupe was founded in 1986 by Cambodian refugee Tim Chan Thou, who had escaped the genocidal Khmer Rouge regime of the 1970s. He and others fled because traditional artists and dancers were specifically marked for death by the Khmer Rouge, which succeeded in killing over 90 per cent of Cambodia's cultural leaders. Those who founded the troupe felt strongly the need to preserve their cultural traditions. More than 500 young people have learned to continue their cultural heritage through dance since the Troupe's founding. In September 2001, the Dance Troupe entered a new chapter in its life by moving to the Mogan Center where it has rehearsal and office space on the third floor.