Susan Magoffin, who was probably quartered here in 1846, was one of the few white women to have seen Bent's Fort. Magoffin was the 18-year-old wife of a prosperous trader and was confined to her room during her stay at the fort, because she had a miscarriage. She wrote of its scenes and activities in her diary from July 27 until she departed on August 7.

Another likely resident of this room was Doctor Hempstead. This man, Edward Lewis Hempstead from St. Louis, had many connections throughout the western fur trade. The Hempstead family acquaintance with the Bents dated back to at least 1808.

The furnishings of this room reflect something of the lifestyle that educated people brought to the frontier. The large rope bed and fancy bedspread, the fine table, the washbasin, and the pitcher have an air of "civilization".